Rheumatoid arthritis physiology

The pathophysiology varies according to diagnosis. Osteoarthritis is a disease most often seen in older individuals but it also may occur in younger people, following injury. The joint consists of bone, cartilage, synovial lining, and ligaments. Subchondral bone is covered by hyaline or articular cartilage that consists of type II collagen, chondrocytes and proteoglycans which are high molecular weight glycoproteins that retain water and increase resiliency of cartilage.

Rheumatoid arthritis physiology

Print For rheumatoid arthritis RAthe most important part of your anatomy to understand is the joints. This article will talk about the joints in your spine that can be affected by RA.

The atlas in the cervical spine is the first vertebra, the one that supports the weight of Rheumatoid arthritis physiology head. Cervical Spine Joints At the top of your spine, where your spine and skull come together, you have the atlas vertebra.

Below the atlas, you have the axis vertebra. It got that name because it helps the atlas rotate, giving the neck incredible mobility. The odontoid process is a tooth-like structure that rises from the body of the axis, and the joint space between the axis and the atlas is termed atlantoaxial.

That is a joint that can be affected by RA.

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The cervical spine also includes the lateral side joints termed zygapophyseal or facet joints. These joints like all joints in your body help facilitate movement and are very important to your flexibility.

The facet joints again, like all joints in your body are covered by cartilage that protects your bones as you move. The cartilage also makes it easier for your bones to move.

The whole joint—cartilage and all—is covered by a thin membrane called the synovium. The synovium produces synovial fluid, which is what truly helps your joints move well. The synovial fluid lubricates the cartilage and bone.

In rheumatoid arthritis, white blood cells can turn against the synovium and cause inflammation.

Rheumatoid arthritis physiology

That inflammation can then lead to the release of certain chemicals that thicken the synovium. The thickened synovium is what causes swollen joints.

Pathophysiology of arthritis pain

It is possible, though. Those spinal regions also have facet joints, just like the cervical spine, so those joints can be affected by RA. You can test your rheumatoid arthritis knowledge with this quiz.Onset of rheumatoid arthritis is usually insidious, often beginning with systemic and joint symptoms.

Systemic symptoms include early morning stiffness of affected joints, generalized afternoon fatigue and malaise, anorexia, generalized weakness, and occasionally low-grade fever.

Joint symptoms include pain, swelling, and stiffness. Rheumatoid arthritis is a chronic disease in which inflammation of the peripheral joints occurs.

Anatomy of Rheumatoid Arthritis

The disease process within the joints begins as an inflammation of the synovium (joint-lining tissue). The disease process within the joints begins as an inflammation of the synovium (joint-lining tissue).

The Future of Rheumatoid Arthritis and Hand Surgery - Combining Evolutionary Pharmacology and Surgical Technique M Malahias, H Gardner, S Hindocha, .

Thus far, rheumatoid arthritis questions in the CICM Fellowship Exam have been mainly interested in the airway problems associated with having temporomandibular joint involvement and cervical spine instability.

Alternatively, the examiners would show the candidates a series of photographs, depicting rheumatoid arthritis of the hands; the question then demanded a list of "hand signs" associated. Rheumatoid arthritis is a chronic disease in which inflammation of the peripheral joints occurs.

The disease process within the joints begins as an inflammation of the synovium (joint-lining tissue). In most cases there is an increase, often considerable, in the amount of synovial. Nov 27,  · Rheumatoid arthritis or RA, is a form of inflammatory arthritis and an autoimmune disease, meaning the body's immune system mistakenly attacks healthy tissue.

This form of arthritis can not be cured, making it a chronic disease.

pathophysiology of rheumatoid arthritis - PMC - NCBI