SN2 and SN1 Reactions: Experiments 6 and 7 Preparation of 1-bromobutane from 1-butanol, 2-chloromethylbutane from 2-methylbutanol Introduction In the name SN1 or SN2, the S stands for substitution.
Hire Writer In the experiment, 1-bromobutane was synthesized through the second order mechanism in the present of concentrated sulphuric acid and sodium bromide. The nucleophile in the experiment is bromide ion Br- while the leaving group is water.
Purification of the product was then obtained by extraction. The principle of extraction as a purification method was based on the difference in solubility between impurities and product.
Identify of the product 1-bromobutane can be confirmed by carrying out sodium iodide in acetone test. The test involves displacement of bromide by iodide.
Since iodide is strong nucleophile which can displace the bromide ion from attached carbon. The reaction was carried out in acetone since acetone dissolved NaI, but not the products NaBr. So the appearance of precipitate and the time it takes to form is the basis for a qualitative test for alkyl halides.
The experiment was divided into three parts and worked in pairs. A Preparation of 1-bromobutane from 1-butanol 1. The exact amount of 1-butanol used was being marked.
The 1-butanol was transferred into a cm3 round-bottomed flask. The beaker was rinsed with 15 mL deioned water and the rinse was put into the round-bottomed flask.
The mixture was cooled in a ice water bath. To the flask in the ice bath, 15 mL of concentrated sulphuric acid was added gently. The flask was swirled to mix the content and a few anti-bumping granules were added. The flask was fitted with the apparatus for reflux on a hot plat with an oil bath; a condenser was placed with tubing connected on top of the round-bottomed flask as shown in figure 1 of the laboratory menu and the join was wrapped with grease.
Checked that water was flowing through the condenser, and then the mixture was heated to reflux. The mixture was allowed to reflux for 45 minutes, during which time mark the observation of the reaction mixture.
After the reflux period, the heat was removed and the mixture was allowed to cool at room temperature. B Purification of 1-bromobutane by extraction 1. The cool mixture was decanted into a mL separatory funnel. The round-bottomed flask was rinsed with small amount of water and the rinse was put into the separatory funnel.
The two layers were allowed to separate and the aqueous later was drained off. The funnel was shaken well in each case.
The gas pressure was released regularly during the shaking. The aqueous layer was discarded down the drain. The organic later was collected into a 50 mL conical flask. To the organic later, about 1 gram of anhydrous magnesium sulphate was added.
The conical flask was swirled thoroughly. The organic layer was filtered using the filter paper and funnel to remove the used magnesium sulphate.
The dry organic extract 1-bromobutane was collected in a pre-weighed beaker and the exact mass of product was obtained. C Test for the product i Sodium iodide in acetone test 1. A few drops of sodium iodide-acetone reagent were added to the test tube 3. The mixture was shaken and let it stand for 3 minutes.
A few drops of bromine-chloroform reagent were added to the test tube.Discussion and Conclusion: Preparation of 1-Bromobutane The purpose of this experiment was to demonstrate the conversion of a primary alcohol, 1-butanol, to a primary bromoalkane, 1-bromobutane.
THE PREPARATION OF 1-BROMOBUTANE FROM 1- BUTANOL Objective ; p-toluenesulfonyl chloride which will convert OH - into sulfonic acid ester to react with sodium bromide to produce 1-bromobutane. Second, we react with the alcohol with phosphorus tribromide CONCLUSION.
The. The purpose of this experiment was to demonstrate the conversion of a primary alcohol, 1-butanol, to a primary bromoalkane, 1-bromobutane, a SN2 reaction.
The conversion of 1-butanol to 1-bromobutane relies on sulfuric acid which plays two important roles. First, it protonates the alcohol of 1-butanol to form an oxonium ion which is a good leaving [ ].
CONCLUSION The experiment was involving second order nucleophilic substituition, attheheels.com 1-Bromobutane was prepared from attheheels.com theoretical yield for this experiment is g while the actual yield is g.
1-butanol 2-butene 1-butene Procedure: In this experiment, my group first set up a simple distillation under the hood. Next, g of sodium bromide was placed in a ml round bottomed flask, along with 10mL of water and g of 1 butanol. The contents were 91%(46). (Preparation of 1-bromobutane from 1-butanol, 2-chloromethylbutane from 2-methylbutanol) Introduction.
In the name S N 1 or S N 2, the S stands for substitution.
One part of the starting molecule is replaced by something else. Discussion and conclusion. There are several significant things about the results of these two experiments.